Addressing Androgenetic Alopecia-A Complex Disorder-with a Multilateral Treatment Strategy

ثبت نشده
چکیده

Androgenetic alopecia (AGA) is a disorder that involves gradual loss of hair in genetically predisposed individuals and is more prominent in men than women. Ethnically, white male are affected the most [1]; the estimated prevalence of AGA in Caucasian populations by the age of 80 is over 90% [2]. Physiological changes which occur during AGA include hair follicle miniaturization and variations in normal hair cycle; specifically, anagen phase length shortens and that of telogen phase stays same or prolongs [3]. In addition, the overall follicular apparatus is also gradually miniaturized which leads to global reduction of hair density due to conversion of terminal hair into vellus hair [4,5].

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Re-activation of Wnt/β-catenin Signaling Pathway in Hair Follicle Stem Cells in Treatment of Androgenetic Alopecia

Hair loss is a common hair disorder in human population. It affects quality of life and there are ongoing attempts to find permanent treatment for this condition. But, today there is no completely safe and protective treatment for all. Hair follicle stem cells are alive, but quiescence in androgenetic alopecia and are potentially active and can proliferate and differentiate, then regenerate hai...

متن کامل

[Androgenetic alopecia in women as an aesthetic and psychological problem].

Androgenetic alopecia is a fairly common disorder which causes serious aesthetic and psychological problems. The paper discusses the etiology, diagnostics and possible treatment of androgenetic alopecia in women. Preparations for both general and external use in treatment of this dermatosis have been presented herein.

متن کامل

Minoxidil in combination with Tretinoin vs. Minoxidil in the treatment of male androgenic alopecia: A randomized, double-blind, parallel clinical trial

Background: Minoxidil is currently an approved treatment for androgenetic alopecia. Topical tretinoin can enhance skin absorption of minoxidil. Objective: This study has been done in order to determine the efficacy and safety of the solution of 0.5% minoxidil+0.05% tretinoin compared to 2% minoxidil in androgenetic alopecia in men. Patients and Methods: In a randomized, double-blind, parallel-g...

متن کامل

Association of androgenetic alopecia and hyperlipidemia

Background an objective: Several studies have indicated that vertex type androgenetic alopecia have a higher-than-normal risk for coronary heart disease but few studies focused on lipid profiles which are important in the pathogenesis of coronary heart disease. This study was designed to investigate the relation between vertex type androgenetic alopecia (Grade III and higher according to ...

متن کامل

Association of androgenetic alopecia and hypertension.

Androgenetic alopecia is considered to be associated with coronary heart disease but the explanation of this association remains unknown. Hypertension is highly prevalent in patients with coronary heart disease. Essential hypertension is linked to hyperaldosteronism and spironolactone, an antihypertensive drug which is a mineralocorticoid receptor antagonist, has been used for a long time in th...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2017